16 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Avascular necrosis ... • Differentiate ... #diagnosis #causes ... #hematology
Gout Tophus on POCUS

Linear transducer about 1cm away from bone/joint, typical of small joint in a
Gout Tophus on POCUS ... 1cm away from bone ... /joint, typical ... clinical #POCUS #ultrasound ... #msk #rheumatology
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Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Non-bloody: OA, avascular ... Like in this case ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
) - MSK Radiology ... interphalangeal joint ... with joint-space ... Differential diagnosis ... #rheumatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
prematurely • risk of joint ... respiratory failure • Neurologic ... loss of teeth • Muscular ... - Pain (muscle/joint ... Phosphatase: • Other causes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... (CVID, WAS), (neurologic ... candidate) - Bone ... not required in all ... #Workup #hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
• Ligament • Bone ... the subchondral bone ... osteopetrosis, avascular ... #Pain #MSK #rheumatology ... approach #workup #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... weeks) Can Be Caused ... #pain #Differential ... #Diagnosis #MSK ... #rheumatology #
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential ... Fever/Chills/Joint ... - Aneurysmal bone ... diagnosis #msk #
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... the face (many differential ... search ANA and aPL ... has been ruled out ... erythematosus #rheumatology