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diagnosis management differential syndrome autoimmune behcet behcets brain cerebritis erythematosus fungal infections infectiousdiseases lesions lupus mycoses myopathy myositis pharmacology ringenhancing
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
lymphoproliferative disease ... • Metastatic disease ... Neuro Behcets Vascular ... differential #diagnosis #causes ... #radiology #neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... basal ganglia, CNS ... and diplopia) • Vascular ... , AS Treatment: ... signs #symptoms #rheumatology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... Arthritis: • Colchicine ... immunosuppressive meds) Vascular ... #pharmacology #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Cerebrovascular Disease ... autoantibodies that will cause ... Erythematosus #SLE #CNS ... #neurology #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulse deficits vascular ... affects the skin, neurologic ... tract, and often causes ... chorioretinitis, CNS ... Differential #Diagnosis #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... • 8%-27% for CNS ... Arthralgia and Arthritis ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... extrapulmonary disease ... especially the CNS ... MC: CNS CSF: • ... Meningitis, septic arthritis
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... nucleotidase 1A (Anti cN ... • Nonerosive arthritis ... statins - probably caused ... /muscular atrophy
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