15 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
knees • Diffuse ... Symptoms: • Cardiac ... calcinosis • Pulmonary ... myositis overlap • Vascular ... Scleroderma #SSc #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Cathepsin G release → vascular ... Imaging: CXR- pulmonary ... Diagnosis: >3 symptoms ... initiation • Differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... ) • Vascular Disease ... Behcet disease) Differential ... management #signs #symptoms ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... pulse deficits vascular ... • Progressive symptoms ... occasional oligoclonal bands ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... bullous or vesicular ... • Cogan Syndrome ... Presentation - Systemic Symptoms ... #diagnosis #rheumatology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Pulse Pressure - Differential ... Pathologic Causes: • Valvular ... disorders - Chronic pulmonary ... Acute Coronary Syndrome ... Infarction • Pulmonary
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Symptoms ... Hyperviscosity, - Vascular ... thrombophlebitis, pulmonary ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... SLE), Sjogren's Syndrome ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
Symptoms • Ocular ... Scleromalacia perforans • Pulmonary ... Rheumatoid nodules, Vascular ... Thrombocytosis, Felty's syndrome ... #diagnosis #rheumatology
Intermittent Bilateral Exophthalmos (Alternating Exophthalmos and Enophthalmos) on Physical Exam

Observing this patient in silence for a
patient- bilateral symptoms ... The syndrome of ... Differentials for ... Commonly, vascular ... Bilateral #clinical #video