11 results
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
Veltassa (Patiromer ... least 3 hours Veltassa ... Veltassa can be ... and potential hypomagnesemia ... #KBinder #Hyperkalemia
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
hypokalemia Patiromer (Veltassa ... Side Effects: Hypomagnesemia ... table #comparison #binders
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... depletion - Phosphorus ... aldosteronism #Hypomagnesemia
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... • Patiromer (veltassa ... cyclosilicate #Potassium #Binders
Phosphate Binders
#Pharmacology #Nephro #Phosphate #Phosphorus #Binders #Comparison #Table #Disadvantages #SideEffects
Phosphate Binders ... Nephro #Phosphate #Phosphorus ... #Binders #Comparison
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... Potassium depletion, Phosphorus ... aldosteronism #Hypomagnesemia
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Antacids, Phosphate Binders ... Algorithm #nephrology #phosphorus
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
absorption (Antacids, Phosphorus ... binders, Niacin
Electrolyte Repletion

Significant electrolyte depletion can result in serious complications. These guidelines are meant to assist with
dL Goal serum phosphorus ... #hypocalcemia #hypomagnesemia
Table 22 provides the characteristics of various phosphate-binding agents.
#Pharmacology #Nephrology #Phosphate #Phosphorus #Binders #Comparison #Table #Disadvantages
Nephrology #Phosphate #Phosphorus ... #Binders #Comparison