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differential oncology management signs arthritis classification leukemia ra rheumatoid vasculitis aion anemia anteriorischemicopticneuropathy aplastic behcet cancer chronic cll cryofibrinogenemia disease
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Tunnel, Sicca Syndrome ... (RA + Neutropenia ... Arthritis #RA #diagnosis ... #rheumatology # ... signs #symptoms
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
altitudinal defect • Fundoscopy ... • Cephalic symptoms ... GiantCellArteritis #GCA #Rheumatology ... Ophthalmology #Diagnosis ... #Algorithm
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... #signs #symptoms ... #rheumatology #
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Algorithm Hodgkin ... pattern of spread, B symptoms ... pathophysiology #Hematology ... #Diagnosis #NonHodgkin
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Difficulty breathing • Neutropenia ... • Improve the symptoms ... Anemia #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... phenomenon CLL Diagnosis ... Cytopenias: • Neutropenia ... • Richter’s Syndrome ... workup #oncology #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... pulmonary emboli, and ocular ... Antiphospholipid syndrome ... #rheumatology # ... hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... or functional neutropenia ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... • Cogan Syndrome ... Differential Diagnosis ... Presentation - Systemic Symptoms ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... #Rheumatology
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