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differential management neurology vasculitis agglutinin anemia antinuclear classification cord hematology hemolytic lupus ms myelitis patterns polychondritis relapsing spinalcord systemic transverse
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... context of other symptoms ... Lymphoproliferative Disorders ... Pulmonary Fibrosis, Multiple ... #rheumatology #diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... infection, autoimmune ... - Mycoplasma, EBV ... CLL (older) • Autoimmune ... chills, flank pain
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
rheumatologic diseases ... Arthritis: • Joint pain ... • Mononeuritis Multiplex ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... Demyelinating: - Multiple ... - SLE, Scleroderma ... MCTD, Sjogren syndrome ... #disorders #diagnosis
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Multiple Sclerosis ... is an autoimmune-mediated ... Sclerosis Diagnosis ... Signs and symptoms ... #sclerosis #diagnosis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
of the spinal cord ... monophasic Pathophysiology ... or without back pain ... /or symptoms • ... Antiamphiphysin antibodies
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
, particularly scleritis ... LFT • ESR • ANA ... ) pattern: antibodies ... SLE) • Urinalysis ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... , particularly scleritis ... ischemia • Skin: Erythematous ... and GN Anti-GBM ... #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cartilage in the body (Autoimmune ... disorder) Who ... Sudden onset of pain ... cases such as: • SLE ... , MDS & Multiple
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