9 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... Lymphoproliferative Disorders ... Pulmonary Fibrosis, Multiple ... ANA #patterns #rheumatology ... #diagnosis #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Syndrome ... infection, autoimmune ... - Mycoplasma, EBV ... pts) Differential ... chills, flank pain
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
rheumatologic diseases ... Arthritis: • Joint pain ... • Mononeuritis Multiplex ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... Demyelinating: - Multiple ... - SLE, Scleroderma ... MCTD, Sjogren syndrome ... #algorithm
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Multiple Sclerosis ... is an autoimmune-mediated ... neurodegenerative disease ... Sclerosis Diagnosis ... #sclerosis #diagnosis
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... or without back pain ... Bilateral signs and/or symptoms ... sclerosis, NMOSD ... management #neurology #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
• Mononeuritis multiplex ... Presentation - Systemic Symptoms ... , particularly scleritis ... vasculitis, and SLE ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
, such as SLE, atherosclerotic ... , particularly scleritis ... claudication, visual ... ischemia • Skin: Erythematous ... #Diagnosis #Rheumatology
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
cartilage in the body (Autoimmune ... disorder) Who ... Sudden onset of pain ... cases such as: • SLE ... , MDS & Multiple