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management agglutinin ana anemia antibodies antinuclear hematology hemolytic lupus ms myelitis patterns polychondritis relapsing spinal spinalcord systemic transverse treatment vasculitis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... Lymphoproliferative Disorders ... Pulmonary Fibrosis, Multiple ... ANA #patterns #rheumatology ... #diagnosis #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... infection, autoimmune ... - Mycoplasma, EBV ... pts) Differential ... chills, flank pain
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... Spinal cord ... - SLE, Scleroderma ... #diagnosis #neurology ... #algorithm
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Multiple Sclerosis ... is an autoimmune-mediated ... Sclerosis Diagnosis ... Progressive MS (Spinal cord ... #sclerosis #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
rheumatologic diseases ... Arthritis: • Joint pain ... • Mononeuritis Multiplex ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... or without back pain ... Bilateral signs and/or symptoms ... #management #neurology ... #differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... , particularly scleritis ... claudication, visual ... ischemia • Skin: Erythematous ... #Diagnosis #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cartilage in the body (Autoimmune ... disorder) Who ... Sudden onset of pain ... cases such as: • SLE ... , MDS & Multiple
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