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differential management neurology agglutinin algorithm anemia erythematosus hematology hemolytic lupus monoarthritis monoarticular ms msk multiple myopathy myositis oligoarthritis oligoarticular polyarthritis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... Agglutinin Syndrome ... infection, autoimmune ... - Mycoplasma, EBV ... chills, flank pain
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis ... Mechanical/degenerative disorders ... constitutional symptoms ... Rheumatologic Disease ... Joint #pain #Differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Non-autoimmune ... rheumatologic diseases ... Joint pain • Swan ... Induced Lupus: • Symptoms ... #Rheumatology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... Framework Spinal cord ... level of spinal cord ... - SLE, Scleroderma ... MCTD, Sjogren syndrome
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... claudication, visual ... • Progressive symptoms ... and GN Anti-GBM ... #Rheumatology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
autoimmune-mediated ... neurodegenerative disease ... Sensitivity to pain ... Signs and symptoms ... Progressive MS (Spinal cord
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cartilage in the body (Autoimmune ... disorder) Who ... Sudden onset of pain ... cases such as: • SLE ... Nonspecific ↑ ESR, CRP, ANA
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... : Fever, joint pain ... • Proximal + distal ... • Nonerosive arthritis ... Myositis #Myopathy #rheumatology
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