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hematology management differential agglutinin anemia apml beriberi causes cold cppd deficiency differentiation disease eosinophilia erythematosus gout hemolytic korsakoff lesions leukostasis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... dizziness, tinnitus, visual ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
- Differential Diagnosis ... aspergillosis) - Viral ... - DRESS - AIN ... Hypereosinophilic Syndrome ... #Causes #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... anterior chest wall, parts ... #Rheumatology # ... diagnosis #management ... #Dermatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... effusions, weight gain ... Differentiation #Syndrome ... #management #hematology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations Causes of Thiamine Deficiency: • Poor intake: - Diets
- Differential Diagnosis ... neuropathy of the distal ... reflexes - Burning pain ... #Differential #Diagnosis ... #nutrition #pathophysiology
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
- Differential Diagnosis ... Mpox • Starts ... SAPHO syndrome ( ... with rheumatic pain ... #Dermatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... CAS): - Due to Viral ... - Polyclonal - Viral ... chills, flank pain ... hemolytic #anemia #hematology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... onset of swelling, pain ... • Metabolic syndrome ... #CPPD #Gout #Comparison ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... Arthritis: • Joint pain ... Erythematosus #Diagnosis ... #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Sudden onset of pain ... Bacterial ○ Viral ... /EGPA • RA Diagnosis ... Polychondritis #rheumatology ... #diagnosis #management
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