19 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... dizziness, tinnitus, visual ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
- Differential Diagnosis ... aspergillosis) - Viral ... - DRESS - AIN ... Hypereosinophilic Syndrome ... #Causes #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... anterior chest wall, parts ... #Rheumatology # ... diagnosis #management ... #Dermatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... effusions, weight gain ... Differentiation #Syndrome ... #management #hematology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... • Weakness: Starts ... Hands or feet • Pain ... Guillain-Barre Diagnosis ... #diagnosis #management
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
- Differential Diagnosis ... neuropathy of the distal ... reflexes - Burning pain ... #Differential #Diagnosis ... #nutrition #pathophysiology
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
- Differential Diagnosis ... Mpox • Starts ... SAPHO syndrome ( ... with rheumatic pain ... #Dermatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... CAS): - Due to Viral ... - Polyclonal - Viral ... chills, flank pain ... hemolytic #anemia #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis via genetic ... agent are the main ... #management #treatment ... #hematology
A prospective randomized, double-dummy trial comparing IV push low dose ketamine to short infusion of low
for treatment of pain ... Visual Abstract ... Infusion #Ketamine #Comparison ... VisualAbstract #Management ... #Pain #EBM