12 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... bacterial and viral ... #Algorithm #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... CTD (SLE) - Viral ... Kasabach-Merritt syndrome ... #hematology #rheumatology ... #nonpalpable #dermatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
to a low blood platelet ... Pinpoint-sized red spots ... neutrophils and platelets ... Neutropenia • Platelet ... #diagnosis #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... Thrombocytopenia - Abnormal platelet ... lesions • Severe pain ... #dermatology #physicalexam
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
- Differential Diagnosis ... aspergillosis) - Viral ... - DRESS - AIN ... Hypereosinophilic Syndrome ... #Causes #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... anterior chest wall, parts ... #Rheumatology # ... #Dermatology
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
- Differential Diagnosis ... Mpox • Starts ... SAPHO syndrome ( ... with rheumatic pain ... #Dermatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... CAS): - Due to Viral ... - Polyclonal - Viral ... chills, flank pain ... hemolytic #anemia #hematology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
symptoms — Headache, visual ... atypical chest pain ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... Arthritis: • Joint pain ... Erythematosus #Diagnosis ... #Rheumatology