WBC anemia microscopy hematology hepatology clinical disease classification pediatrics sicklecellanemia

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Treatments for Sickle Cell disease

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM #FOAMed

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Cures for Sickle Cell disease

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Complications of Sickle Cell Disease slide 1/3

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM

of Sickle Cell Disease ... sicklecelldisease #sicklecellanemia ... sicklecells #sickle #hematology ... #anemia #clinical ... #pediatrics #FOAM

Complications of sickle cell disease slide 2/3

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics

of sickle cell disease ... sicklecelldisease #sicklecellanemia ... sicklecells #sickle #hematology ... #anemia #clinical ... #pediatrics #FOAM

complications of sickle cell disease slide 3/3

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM

of sickle cell disease ... sicklecelldisease #sicklecellanemia ... sicklecells #sickle #hematology ... #anemia #clinical ... #pediatrics #FOAM

Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),

Iron deficiency anemia ... anemia (sometimes ... Sideroblastic anemia ... differential #diagnosis #hematology ... #microscopy #atlas

Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
• Acute Bleed - Normocytic / Normochromic

Overall Approach to Anemia ... • Anemia of Chronic ... Disease • Marrow ... #Classification ... Algorithm #Causes #Hematology

Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red

Megaloblastic Anemia ... cells: Sickle cell disease ... Smear #Analysis #hematology ... #microscopy #interpretation ... #clinical #anemia

Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and

Normal: < 1% Clinically ... • Autoimmune diseases ... Even with normal WBC ... likelihood of negative clinical ... #CBC #hematology

Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
1. Cold Agglutinins (CAD)
2. Donath-Landsteiner

Viral Infection Clinical ... • Symptoms of anemia ... • hemolytic anemia ... Blood smear - RBC ... #hematology #diagnosis

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