WBC anemia microscopy hematology hepatology clinical disease classification pediatrics sicklecellanemia approach

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Treatments for Sickle Cell disease

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM #FOAMed

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Cures for Sickle Cell disease

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM #FOAMed

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Complications of Sickle Cell Disease slide 1/3

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM

of Sickle Cell Disease ... sicklecelldisease #sicklecellanemia ... sicklecells #sickle #hematology ... #anemia #clinical ... #pediatrics #FOAM

Complications of sickle cell disease slide 2/3

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics

of sickle cell disease ... sicklecelldisease #sicklecellanemia ... sicklecells #sickle #hematology ... #anemia #clinical ... #pediatrics #FOAM

complications of sickle cell disease slide 3/3

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM

of sickle cell disease ... sicklecelldisease #sicklecellanemia ... sicklecells #sickle #hematology ... #anemia #clinical ... #pediatrics #FOAM

Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
• Acute Bleed - Normocytic / Normochromic

Overall Approach ... Disease • Marrow ... #Classification ... #Approach #Differential ... Algorithm #Causes #Hematology

Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),

Iron deficiency anemia ... iron deficiency anemia ... Autoimmune hemolytic anemia ... differential #diagnosis #hematology ... #microscopy #atlas

Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red

Megaloblastic Anemia ... cells: Sickle cell disease ... Smear #Analysis #hematology ... #microscopy #interpretation ... #clinical #anemia

Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
• Thalassemia

Algorithmic Approach ... to Anemia - Differential ... Spherocytosis, G6PD, PK, HbC ... Non-megaloblastic: Liver disease ... Differential #Diagnosis #hematology

Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and

Normal: < 1% Clinically ... • Autoimmune diseases ... Even with normal WBC ... likelihood of negative clinical ... #CBC #hematology

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