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diagnosis hematology oncology differential deficiency treatment signs syndromes chronic cll infections leukemia lymphocytic pathophysiology pulmonary agglutinin aids algorithm allergy antibiotics
Risk Factors and Signs of Copper Deficiency Risk Factors: • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
diarrhoea, Short bowel syndrome ... /jejunal nutrition ... Haematological: Anaemia ... #riskfactors #symptoms ... #nutrition
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management Diagnosis - Caine Criteria (2 of
Diagnosis and Management ... upper limb) • Nutritional ... treatment can improve symptoms ... development of Korsakoff syndrome ... Deficiency #Diagnosis #Management
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
E - Haemolytic anaemia ... Wernicke-Korsakoff syndrome ... Vitamin B12 - Anaemia ... diagnosis #signs #symptoms ... #nutrition
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... • Improve the symptoms ... hematology #diagnosis #management
Refeeding Syndrome: Pathogenesis and clinical findings Patients at Risk of Refeeding Syndrome: - Little or no nutritional
Refeeding Syndrome ... - Little or no nutritional ... Serum PO4 -> decr RBC ... hemolysis - anemia ... pathophysiology #symptoms
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... Dehydration • Symptoms ... changes, stroke symptoms ... • Lab values: WBC ... TLS #diagnosis #management
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
to manifest its symptoms ... , alcohol use, symptoms ... • Labs: - CBC ... Deficiency #diagnosis #management ... #nutrition
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... of anemia include ... • hemolytic anemia ... Blood smear - RBC ... disease #hemolytic #anemia
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Vmphocytosis on routine CBC ... of anemia or thrombocytopenia ... Constitutional symptoms ... marrow failure with anemia ... hemeonc #diagnosis #management
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
Diagnosis and Management ... breath, wasting, anemia ... musculoskeletal symptoms ... Psychiatric symptoms ... Loss of teeth Anemia
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