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differential alp causes cirrhosis dermatology generalized hepatitis lfts management oncology phosphatase primary secondary systemic abnormal aih autoimmune biliary chemistry cholangitis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... - Fatigue - Pruritis ... biliary Cholangitis (PBC ... #Algorithm #hepatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Differential Diagnosis ... Algorithm - Systemic ... / Systemic == Blood ... & BUN: • Chronic
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
cholestasis → Cirrhosis/Liver ... asymptomatic • Pruritus ... Labs: • Alkaline ... or higher • Liver ... #workup #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
tests algorithm ... magnitude of enzyme elevation ... body mass index; FBC ... disease; T2DM, ... #Hepatology #Liver
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... • NASH, Chronic ... intestines, white blood ... #algorithm #hepatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Algorithm Blood ... & BUN: • Chronic ... Hyperthyroidism CBC ... #generalized #dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... : Acute blood loss ... • Infections: Chronic ... #Algorithm #hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
disease: > 2 ... • NASH, Chronic ... intestines, White blood ... #chemistry #diagnosis ... #differential #Hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver ... thigh bones -> chronic ... Malnutrition • Wilson's disease ... deficiency • blood ... Hyophosphatasia #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
from subclinical disease ... - Symptoms of chronic ... (rare) - IgG Elevation ... regarding need for treatment ... #Management #Hepatology
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