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anemia causes hemolytic liver hemolysis lfts approach chemistry cold elevatedmcv extravascular hepatitis hodgkins injury interpretation intravascular lymphoma macrocytic macrocytosis oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Diagnosis Algorithm ... Normal Blood Smear ... WBCs - Normal ... #Diagnosis #Algorithm ... #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm ... Blood Loss ... Anemia of Chronic Disease ... #Diagnosis #Algorithm ... #Causes #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Syndrome (CAS): ... smear - RBC agglutination ... younger pts) Differential ... sensitize red blood ... #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... deficiency, Other enzyme ... membrane disorder ... #Diagnosis #Algorithm ... #workup #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... , Spiders - Enzyme ... - Peripheral Blood ... Smear ↑ abnormal ... #Diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
. primary cold agglutin ... disorders, Mycoplasma ... Defects: Enzyme ... Extravascular #Causes #differential ... #diagnosis #hematology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
tests algorithm ... presence of metabolic syndrome ... #Algorithm #Hepatology ... #Liver #Enzymes ... #Differential #
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Diagnosis Algorithm ... function may be abnormal ... Source of Liver Enzyme ... #diagnosis #algorithm ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Source of Liver Enzyme ... intestines, White blood ... • Gilbert's syndrome ... #differential # ... Hepatology #transaminitis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... platelets - WBC ... number of sites of disease ... #hematology #oncology ... #management
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