14 results
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
Autoagglutination ... #Clinical #Pathology ... #Blood #Smear # ... Microscopy #Rouleaux ... #Formation #Hematology
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
cold agglutinin disease ... individual’s red blood ... #Clinical #Path ... #Blood #Smear #Microscopy ... #RBC #Autoagglutination
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
cold agglutinin disease ... individual’s red blood ... #Clinical #Path ... #Blood #Smear #Microscopy ... #RBC #Autoagglutination
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... cells: Sickle cell disease ... #hematology #microscopy ... interpretation #clinical
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Algorithm Normal Blood ... Smear • Drugs ... RBCs in Rouleaux Formation ... Cells, Normal WBCs ... Algorithm #Causes #Hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... arrow) Peripheral smear ... #Hematology #Pathology ... #Smear #Microscopy
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... of peripheral blood ... • Autoimmune diseases ... #CBC #hematology ... #pathophysiology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Immunoglobulin M (IgM) • Blood ... smear - RBC agglutination ... sensitize red blood ... #hematology #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... protein C and S Pathophysiology ... organ damage Clinical ... • Peripheral smear ... • Severe Liver Disease
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
Smear 23M Somali ... Hgb 12.5, WBC 14 ... Infectious Diseases ... recurrentis #BloodSmear #microscopy ... #pathology #clinical