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management anemia intravascular aplastic cell chronic cll coagulation dic hemolysis hemolytic hodgkins leukemia lymphocytic lymphoma mds myelodysplasia myelodysplastic plasmacytoma solitary
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Causes Intravascular ... anemia): - Disseminated ... #Causes #differential ... #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... organ damage Clinical ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... reflection of intravascular ... from ischemia WBC ... count and differential ... #Workup #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Hodgkin Lymphoma Workup ... platelets - WBC ... Hodgkin Lymphoma Treatment ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... • ↓ WBC • ↓ ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Lymphocytosis on CBC ... microglobulin Treatment ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... Bone marrow Treatment ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology
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