11 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
primary biliary cholangitis ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing ... #workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... smear, HIV/HCV testing ... pylori test (GI symptoms ... #Diagnosis #Causes ... #Workup #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... Signs and Symptoms ... bile ducts Differential ... #cholangitis #diagnosis ... #workup #hepatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Diagnosis: • hemolytic ... Blood smear - RBC ... younger pts) Differential ... #hematology #diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... • Coombs (-) hemolytic ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Imaging: CXR- pulmonary ... : >3 symptoms, or ... initiation • Differential ... #management #hematology ... #oncology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Caused by intrapulmonary ... Testing: • Pulse ... resolution of symptoms ... #diagnosis #management ... #treatment #hepatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune system ... with no early symptoms ... cells can indicate disease ... #workup #oncology ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... Diagnosis: Systemic ... Symptoms (Sx) in ... Lab Tests: • CBC ... #diagnosis #rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... Hodgkin Lymphoma Workup ... platelets - WBC ... classification #hematology ... #oncology #management