13 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... if high risk if WBC ... QD until normal WBC ... #management #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Lymphocytosis on CBC ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Intraoperative Sepsis - Guidelines for Crises in Anaesthesia

Severe sepsis (hypotension persisting after initial fluid challenge of
Intraoperative Sepsis ... gas, lactate, FBC ... anaesthesia #Sepsis #Anesthesiology ... #Checklist #Diagnosis ... #Management #Workup
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Local Anaesthetic Toxicity - Guidelines for Crises in Anaesthesia
Signs of severe toxicity:
 • Sudden alteration in
without tonic-clonic ... Anaesthetic #Toxicity #Anesthesiology ... #Anesthesia #Intraoperative ... #Checklist #Diagnosis ... #Management #Workup
Intraoperative Hypertension - Guidelines for Crises in Anaesthesia
Hypertension is most commonly due to inappropriate depth of
Intraoperative Hypertension ... overload / TURP syndrome ... #Hypertension #Anesthesiology ... #Checklist #Diagnosis ... #Management #Workup
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Marrow Failure • Chronic ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
mins, U&E, CK, FBC ... Hyperthermia #Crisis #Anesthesiology ... #Anesthesia #Intraoperative ... #Checklist #Diagnosis ... #Management #Workup
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
3 questions to work ... correction of chronic ... demyelination syndrome ... #Treatment #management ... #nephrology #sodium