11 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
(PBC) - Summary ... PBC Epidemiology ... 30-65 years PBC ... • Fatigue PBC ... #diagnosis #workup
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Diagnosis Algorithm ... Neutrophils - Low RBC ... Myelodysplastic Syndromes ... #Diagnosis #Algorithm ... #Causes #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Diagnosis Algorithm ... Autoimmune hepatitis, PBC ... stone, Malignancy, PBC ... • Bilirubin: RBC ... • LDH: Heart, RBC
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... hypertension • Unusual RBC ... acanthocytes - Consider RBC ... Diagnosis #Algorithm ... #workup #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
CMV) • Epstein-Barr ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... #oncology #hematology ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... if high risk if WBC ... QD until normal WBC ... #management #hematology ... #oncology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... - NORMAL CSF WBC ... #Syndrome #diagnosis ... #management #treatment
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
+Organomegaly+↑RBC ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... • Neutropenia, anemia ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Hodgkin Lymphoma Workup ... platelets - WBC ... Immunohistochemical studies (to differentiate ... #oncology #management