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differential sle causes dermatology erythematosus generalized oncology pruritus secondary signs classification cll comparison leukemia lymphocytic monoclonal paraproteinemias primary sarcoidosis vasculitides
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... Abdominal pain (20%) Renal ... ) Blood (75%): Anemia ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Algorithm - Systemic ... Creatinine & BUN: • Chronic ... renal failure/uremia ... Hyperthyroidism CBC ... Myelodisplastic syndrome
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
months to years) Systemic ... • Evolution: Chronic ... Lupusreference #druginduced ... #table #rheumatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... APLA/LAC: • Renal ... : • Symptoms limited ... : • Chronic B-cell ... #Diagnosis #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(-) hemolytic anemia ... to cold IgG • Lupus ... vascular beds-renal ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Creatinine & BUN: • Chronic ... renal failure/uremia ... Hyperthyroidism CBC ... Myelodisplastic syndrome ... Pruritus #secondary #systemic
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... the lymphatic system ... , and possibly renal ... but stable or chronic ... skin (16-32%): lupus
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... rendering the immune system ... with no early symptoms ... • Neutropenia, anemia ... workup #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... Eosinophilia, asthma, chronic ... lupus erythematosus ... Symptoms (Sx) in ... #rheumatology #
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