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differential causes approach arthritis cholangitis gap globulin hemolytic hodgkins laboratory lymphoma oncology platelet primary protein proteingap rheumatic rheumatoid thrombocytopenia thrombocytosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... Autonomous: • Essential ... • Rheumatic disorders ... • Celiac disease ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
RBCs Decreased RBC ... • Anemia of Chronic ... Disease • Marrow ... #Classification ... #Hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... Pathophysiology ... : • Viral hepatitis ... #Cirrhosis #PBC ... #workup #hepatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
hypertension • Unusual RBC ... acanthocytes - Consider RBC ... membrane disorder ... #Algorithm #workup ... #hematology #testing
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
decreased PLT count: CBC ... smear, HIV/HCV testing ... gastric bypass), LFT ... , HBsAg/anti-HBc ... #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Complete blood count (CBC ... function tests (LFTs ... #diagnosis #testing ... #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... : Cirrhosis, ETOH ... , PBC, PSC, Viral ... gastric tumors • Hematology ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Hodgkin Lymphoma Workup ... platelets - WBC ... #hematology #oncology ... #management
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