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anemia chronic differential hemolytic intravascular lymphocytic aplastic classification cold dic disseminated extravascular gap globulin hemeonc hemolysis hodgkins lymphoma mgus multiplemyeloma
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
marrow plasma cell ... , B and T cell lymphoproliferative ... diseases, CML, ... MGUS #diagnosis ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Diagnosis: • ... can indicate disease ... adult T cell leukemia ... #oncology #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoid malignancy (CLL ... malignancies - B-cell ... malignancies -> CLL ... significance (MGUS), CLL ... #anemia #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... ) (e.g. lupus, CLL ... . primary cold agglutin ... Hemoglobinopathies (e.g. sickle cell ... #hematology #anemia
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... Transformation to large cell ... uw_IMresidency #CLL ... #oncology #hematology ... #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... organ damage Clinical ... • Severe Liver Disease ... #diagnosis #causes ... #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Causes of Monoclonal ... myeloma • Plasma cell ... gastric tumors • Hematology ... Thalassemia, Sickle cell ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... virus (EBV) • Leukemia ... #hematology #diagnosis ... #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... platelets - WBC ... number of sites of disease ... classification #hematology ... #oncology #management
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