86 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Abnormal peripheral smear ... • Extrinsic RBC ... • Intrinsic RBC ... Diagnosis #Algorithm #hematology
Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... Bodies #Pathology #Hematology ... #Smear #Clinical
Diagnosis of active multiple myeloma is not just CRAB; it's actually "SLiM CRAB" @Majorajay & @Vincentrk

#MultipleMyeloma
CRAB #SLIMCRAB #Oncology ... #HemeOnc #Hematology ... Hypercalcemia #Anemia ... #Clinical #Diagnosis
Algorithm for diagnosis of familial thrombocytopenia. Platelet size, best determined by review of the peripheral smear,
diagnosis of familial thrombocytopenia ... the peripheral smear ... #Diagnosis #Hematology ... #Familial #Thrombocytopenia
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Testing in Hemolytic Anemia ... LDH Peripheral smear ... #Hemolytic #Anemia ... workup #diagnosis #hematology
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Idiopathic Thrombocytopenic ... Purpura Clinical ... ITP #Idiopathic #Thrombocytopenic ... #Purpura #Thrombocytopenia ... Diagnosis #Overview #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Normochromic RBCs on Smear ... • Anemia of Chronic ... Spherocytes on Smear ... Algorithm #Causes #Hematology
Pathophysiology of Hemolytic Anemia
 - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects)
 -
Pathophysiology of Hemolytic Anemia ... - Defects in RBC ... - Defects in RBC ... Pathophysiology #Hemolytic #Anemia ... #hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... Peripheral #Blood #Smear ... #Analysis #hematology ... interpretation #clinical ... #anemia
Leukoerythroblastosis and myelophthisic anemia can be associated with any marrow-replacing process. In this case, the likely
myelophthisic anemia ... Leukoerythroblastosis #Hematology ... #Pathology #Smear ... #Microscopy #Clinical