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diagnosis lfts causes hepatitis transaminitis alkaline autoimmune blood chemistry cholangitis cirrhosis disorders elevated elevation enzymes gap globulin interpretation liverenzymes liverfunctiontests
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Autoimmune hepatitis, PBC ... stone, Malignancy, PBC ... function may be abnormal ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Ducts - PBC ... - CBD stone, Biliary ... #diagnosis #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... Pathophysiology ... bile ducts Differential ... cholangitis #diagnosis #workup ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... biliary obstruction ... Malignancy, 1° PBC ... #Injury #Differential ... #algorithm #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Diagnosis Algorithm ... Cholangitis (PBC ... biliary diseases ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
• Bilirubin: RBC ... cardiac muscle, RBC ... • LDH: Heart, RBC ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Drugs • AIH ... • Cholestatic disease ... Duct Stone • Biliary ... Others #LFTs #Hepatology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Acute • Myloid ... • Lymphoid (ALL ... bcr-able (+) ↑ WBC ... bcr-able (-) - Polycythemia ... Blood #Disorders #hematology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
from subclinical disease ... to acute liver ... injury, though ... been reported (eg AIH-PBC ... Diagnosis #Management #Hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... include extrahepatic biliary ... body mass index; FBC ... #Algorithm #Hepatology ... #Differential #
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