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diagnosis differential algorithm pbc biliary management alp ascites hepatopulmonary hypertension phosphatase portal syndrome treatment workup abdominal alkphos astalt bilirubin caput
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary ... Biliary Cirrhosis ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... Pathophysiology ... intralobular bile ducts causes ... Labs: • Alkaline ... diagnosis #workup #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Highest • Bone • Liver ... Intestine - Other causes ... - Drugs - Primary ... biliary Cholangitis (PBC ... Diagnosis #Algorithm #hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Etiologies of Cirrhosis ... congenital - Primary ... Nonalcoholic fatty liver ... #Differential #Hepatology ... #Cirrhosis #Causes
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 Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... #Primary #Biliary ... #Cirrhosis #Pathophysiology ... #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... Liver biopsy findings ... #PBC #Primary ... Diagnosis #Algorithm #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Malignant • Primary ... Non-Malignant • Fatty Liver ... Biliary Cirrhosis ... Diagnosis #Algorithm #Causes ... #Hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
: INR/PT, aPTT(liver ... bypass), LFT (liver ... unclear, or if a primary ... hematologic disorder ... #Workup #hematology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
to non-cirrhotic ... sarcoidosis) • Liver ... metastasis • Fatty liver ... pregnancy • Primary ... #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Tests - AST, ALT, Alkaline ... CAST) • ALT: primarily ... within liver Alkaline ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology
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