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causes dermatology lfts oncology primary pruritus secondary apml biliary chemistry cholangitis differentiation elevatedmcv globulin hepatitis injury interpretation liverfunctiontests macrocytic macrocytosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
with elevated Mean ... Diagnosis Algorithm ... WBCs - Normal ... #Diagnosis #Algorithm ... #Causes #Hematology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Diagnosis Algorithm ... #Abnormal #Transaminitis ... #Algorithm #diagnosis ... #hepatology #LiverFunctionTests
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis ... Algorithm - Systemic ... Myelodisplastic syndrome ... #generalized #dermatology ... Diagnosis #Algorithm
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... /Liver failure ... or slightly elevated ... bile ducts Differential ... #hepatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Diagnosis Algorithm ... Myelodisplastic syndrome ... Pruritus #secondary #systemic ... #generalized #dermatology ... Diagnosis #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Diagnosis Algorithm ... specificity to elevated ... function may be abnormal ... #diagnosis #algorithm ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
specificity to elevated ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... Sarcoidosis) • Liver ... disease: Cirrhosis ... gastric tumors • Hematology ... #diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Erythema elevatum ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... > 5 or elevated ... initiation • Differential ... #management #hematology
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