9 results
diagnosis algorithm anemia causes generalized oncology pruritus workup cold disease extravascular hemolysis hodgkins intravascular lymphoma management monoclonal normocytic paraproteinemias polycythemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... lymphoproliferative disorder Secondary ... Blood smear - RBC ... younger pts) Differential ... #anemia #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Hypersplenism • Secondary ... Normal/lncreased WBCs ... Bleed • Hemolysis ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... . primary cold agglutin ... • Intrinsic RBC ... Extravascular #Causes #differential ... #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Agglutination - Cold agglutinins ... #Anemia #Differential ... Algorithm #workup #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
- Generalized Differential ... Hyperthyroidism CBC ... & Differential: ... Pruritus #primary #secondary ... #dermatology #Differential
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Hyperthyroidism CBC ... & Differential: ... #Pruritus #secondary ... #systemic #generalized ... #dermatology #Differential
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
neuropathy) • Systemic ... +Organomegaly+↑RBC ... • Coombs (-) hemolytic ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... frequently affected systems ... Better call hematology ... else is driving RBC ... Algorithm #workup #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... -95% of cases) Classification ... platelets - WBC ... Immunohistochemical studies (to differentiate ... #hematology #oncology
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