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hematology differential elevatedmcv hemolysis intravascular chronic cll gap globulin hemolytic leukemia leukostasis lymphocytic lysis macrocytic management microcytic oncology protein proteingap
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Algorithm Extravascular ... immune-complex hemolytic anemia ... #Algorithm #Causes ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Myelodysplastic Syndromes ... Cells, Normal WBCs ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Causes Intravascular ... • Intrinsic RBC ... #diagnosis #hematology ... #anemia
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Algorithm Decreased ... #Macrocytosis # ... #Algorithm #Causes ... #Hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... count cause hyperviscosity ... >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Lymphocytosis on CBC ... • Neutropenia, anemia ... • Richter’s Syndrome ... workup #oncology #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... Liver disease: Cirrhosis ... gastric tumors • Hematology ... #differential #diagnosis ... #hematology
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