10 results
hematology leukemia cll lymphocytic aplastic common cvid differentiation essential et hemeonc hypogammaglobulinemia immunodeficiency immunology leukostasis lysis mds myelodysplasia myelodysplastic polycythemiavera
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... #APML #diagnosis ... #management #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
: Blast crises ... - infiltrates (anemia ... smear: Blasts APML ... Transformation: • Complication ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Physical Exam/Signs ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... #oncology #hematology ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... count cause hyperviscosity ... >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... 5) Symptoms of anemia ... thrombocytopenia Complications ... Lymphocytic #Leukemia #oncology ... #diagnosis #management
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management ... incidentally via CBC ... present, symptoms, signs ... , and complications ... • Treatment algorithms
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Out Secondary Causes ... Marrow Failure • Chronic ... #diagnosis #hematology ... #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
noninfectious complications ... Autoimmunity • Chronic ... autoimmune hemolytic anemia ... DDX - Other causes ... #diagnosis #management
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
(ET) ET is a chronic ... Most cases are related ... , symptoms and complications ... • Treatment algorithms ... #diagnosis #management
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