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biliary pbc primary alkaline alp differential elevation hematology leukostasis lysis management phosphatase syndrome tls tumor workup
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... intralobular bile ducts causes ... Signs and Symptoms ... #PBC #cholangitis ... #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
- Diagnosis Algorithm ... Symptoms: Fatigue ... quadrant discomfort Signs ... #Diagnosis #Algorithm ... #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Algorithm ALP ... Intestine - Other causes ... Primary biliary Cholangitis ... (PBC) - Other ... #Algorithm #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... count cause hyperviscosity ... • Lab values: WBC ... >100k, + lab signs ... Syndrome #TLS #diagnosis
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