WBC pathophysiology hematology clinical skinrash diagnosis anemia systemic causes signs algorithm drugreaction syndrome sle eosinophilia vasculitis

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Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents

and Systemic Signs ... (DRESS Syndrome ... medication (in this case ... #Dermatology #SkinRash ... #DrugReaction #

Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin

Clinical Features ... Butterfly rash, Vasculitis ... ) Blood (75%): Anemia ... #signs #symptoms ... #diagnosis #rheumatology

Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
•

• EGPA: - Eosinophilia ... tract, and often causes ... purpura: strong sign ... , and SLE) • Urinalysis ... #rheumatology #

Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,

Diagnosis Framework ... diseases, such as SLE ... purpura: Strong sign ... tract, and often causes ... #Rheumatology

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

SLE (Systemic Lupus ... ) Suspect: Clinical ... Differential Diagnosis ... Clinical Features ... lymphopenia, low PLT • Anemia

Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
• Lymphocytes accumulate in large numbers

rendering the immune system ... Orange or Hep C Clinical ... Physical Exam/Signs ... • Neutropenia, anemia ... workup #oncology #hematology

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