3 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
if high risk if WBC ... HoTN, edema and effusions ... initiation • Differential ... Anaphylaxis, Acute Renal ... QD until normal WBC
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
coagulopathy) • CBC ... LVEF, pericardial effusion ... sparing of the lung ... gross hematuria, RBC ... #Syndromes #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... : • Pleural effusions ... : • Joint pain ... APLA/LAC: • Renal ... titers > 1:80 • CBC