9 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Membrane): - Autoimmune ... Drug-associated, PCH, Evans Syndrome ... Laboratory Tests ... #Diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... C Clinical Presentation ... Paraneoplastic phenomenon ... CLL Diagnosis ... workup #oncology #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... younger pts) Differential ... test #cold # ... hemolytic #anemia #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... vein: Budd-chiari syndrome ... extrahepatic source - Tests ... #hepatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... -12%), Raynaud phenomenon ... #Rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... rheumatologic diseases ... Clinical Features ... #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... Tests: • Measure ... weakness + atrophy- Hip ... Myositis #Myopathy #rheumatology ... #differential #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
changes (POEMS syndrome ... Cirrhosis, ETOH, autoimmune ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
cartilage in the body (Autoimmune ... Males • Affects all ... the most common clinical ... : • Clinical tests ... Polychondritis #rheumatology