10 results
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
- Compatible syndrome ... + MRI lesions + ... nodules, may also see ... #Brain #differential ... #radiology #neurology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
bilateral white matter lesions ... well-defined than PML lesions ... Diagnosis: MRI ... syndrome of HAD ... dementia #AIDS #Neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Space occupying lesions ... Brain tumor • Lesions ... Lesions Of The Peripheral ... EMG) studies • MRI ... #Diagnosis #neurology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
PHANTOMS): • Pattern ... history of cancer, HIV ... Space-occupying brain lesion ... • CNS infection ... #neurology #PHANTOMS
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... parietal - Size lesions ... Enhancement: multifocal lesions ... punched-out" cystic lesions ... InfectiousDiseases #Neurology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
BEE Syndromes - ... nervous system (CNS ... pachymeningitis • HIV ... lesions and clinical ... #Syndromes #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... compressive cord lesion ... less swollen - Lesion ... or optic nerve lesions ... #management #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Imaging Patterns ... showing cortical lesions ... Reversible course Differential ... #Syndrome #diagnosis ... #management #neurology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... demyelinating lesions ... resonance imaging [MRI ... ] T2 lesions) McDonald ... #management #neurology
One and a Half Syndrome on Physical Exam

This 28 year old patient presented to clinic with
One and a Half Syndrome ... been fluctuating ... results from a lesion ... with MS, and started ... ophthalmology #neurology