22 results
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Reticulocytosis • Primary ... Hypersplenism • Secondary ... Diagnosis #Algorithm #Causes ... #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
15% of AIHA Primary ... Secondary Cold ... Syndrome (CAS): ... Blood smear - RBC ... #hematology #diagnosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Myelodysplastic Syndromes ... Cells, Normal WBCs ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... changes), high MCV anemia ... unclear, or if a primary ... #Workup #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Causes == Primary ... renal failure/uremia ... Hyperthyroidism CBC ... Myelodisplastic syndrome ... #secondary #systemic
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Cirrhosis (PBC) ... Pathophysiology ... intralobular bile ducts causes ... #diagnosis #workup ... #hepatology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... Post-splenectomy Primary ... Myelodysplastic syndrome ... #hematology #secondary
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgM) (e.g. primary ... cold agglutin disease ... differential #diagnosis #hematology ... #anemia
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
/Quantity: • Primary ... - Hemolytic anemia ... deficiency • Liver ... Differential #Diagnosis #hematology ... #rheumatology #
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... discoloration) • Liver ... cirrhosis • Congestive ... • Nephrotic syndrome ... Diagnosis #Algorithm #causes