58 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count ... Dehydration • Symptoms ... • Lab values: WBC ... #TLS #diagnosis ... #management #hematology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Visual or auditory symptoms ... conjunction with symptoms ... and treatment can ... clinical consistent ... with MS • Other
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... if high risk if WBC ... : >3 symptoms, or ... : Infection (sepsis
Problem Representation - Approach to the Infectious Disease Patient

Who: Patient age and host/risk factors (such as
Approach to the Infectious ... symptoms that define ... the clinical syndrome ... febrilepodcast@gmail.com #InfectiousDiseases ... #History #HPI #Diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Clinical Presentation ... Blood smear - RBC ... hemolytic #anemia #hematology ... #diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... • ↓ WBC • ↓ ... aplastic anemia Treatment ... • Improve the symptoms ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... symptoms can mimic ... common infections ... #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... WBC >2000 in synovial ... effusion with few WBCs ... constitutional symptoms ... #MSK #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... immunophenotype Clinical ... Complications: 1) Infection ... lymphadenopathy and ... #hemeonc #diagnosis
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
- Differential Diagnosis ... cells per μL • Diagnosis ... should be based on clinical ... Antimicrobial treatment ... opportunistic #InfectiousDiseases