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anemia hemolysis hemolytic intravascular oncology agglutinin bee chronic classification cold common cvid gap globulin hemeonc hodgkins hypogammaglobulinemia immunodeficiency immunology injury
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Causes Intravascular ... , lymphoma, idiopathic ... #Causes #differential ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Diagnosis Algorithm ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... lymphoma (Richter ... AIHA, PRCA) • Treatment ... Leukemia #oncology #hematology ... #management
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Diagnosis Algorithm ... Vascular Causes ... Autoimmune hepatitis ... diagnosis #algorithm ... #hepatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
women • 15% of AIHA ... disorder or lymphoid ... Viral Infection Clinical ... pts) Differential ... hemolytic #anemia #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... and hepatitis ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
- Clinical Presentation ... platelets - WBC ... Treatment • Early ... #hematology #oncology ... #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... hepatitis, primary ... phenomenon (16%) MSK ... • B cell lymphoma ... #Diagnosis #Management
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
an underlying autoimmune ... and treatment can ... Malignant • Lymphoma ... neuropathy (LHON) plus MRI ... lesions and clinical
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
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