14 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Blood Loss ... Decreased RBC ... Deficiency • Aplastic ... of Chronic Disease ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... lymphoproliferative disorders ... • Intrinsic RBC ... #differential # ... diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Normal Blood Smear ... Neutrophils - Low RBC ... Myelodysplastic Syndromes ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
decreased PLT count: CBC ... (CVID, WAS), (neurologic ... ), HBsAg/anti-HBc ... Diagnosis #Causes ... #Workup #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Diagnosis: • hemolytic ... smear - RBC agglutination ... #hemolytic #anemia ... #hematology #diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... anemia Treatment ... #hematology #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... prevention (statin for CVA ... #neurology #rheumatology ... #management #treatment
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Diagnosis: Causes ... acidosis: - CNS ... sedation, narcotics, CVA ... #Summary #Nephrology ... #ABG #bloodgas
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
+Organomegaly+↑RBC ... Scleromyxedema (CNS ... +GI+CVS+joints) ... • Amyloidosis (CVS ... Paraproteinemias #Hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Leukocyte reduced RBC ... Gamma-irradiated RBC ... Volume Reduced RBC ... • Washed RBC ... #management #hematology