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hematology blood product reactions anemia chronic classification encephalopathy extravascular hemolysis hodgkins hyperkalemia intravascular k leukemia lymphocytic lymphoma mds myelodysplasia myelodysplastic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... • Intrinsic RBC ... #differential # ... diagnosis #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... due to marrow aplasia ... products contain potassium ... #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
due to marrow aplasia ... products contain potassium ... Infection - Infection ... #diagnosis #management ... #hematology #reactions
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... cells can indicate disease ... aplasia • ITP ... microglobulin Treatment ... #workup #oncology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
, transfusions), ... draw, ↑↑Plts or ↑↑WBC ... Elimination (see Table ... #Management #Treatment ... #potassium #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
disease 2. ... Monitor potassium ... #Diagnosis #Management ... #causes #treatment ... #nephrology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Anemia • Aplastic ... Myeloproliferative Disease ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... nodosum • Immune hemolytic ... Hodgkin Lymphoma Workup ... platelets - WBC ... #oncology #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Shock, Autoimmune disease ... emergency, Blood transfusion ... Reversible course Differential ... • Treatment of ... #management #neurology
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