11 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Pain Rash ... • Rheumatic fever ... #joint #pain #skin ... #rashes #differential ... #diagnosis #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusion ... Fever/Chills/Joint ... pain/Night sweats ... Infectious Knee ... arthritis - SLE
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
) General: Fever ... Sjögrens (15%) Skin ... 50%): Pleurisy / effusion ... (20%) Renal disease ... #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... - Hemolytic anemia ... Anticoagulants (Warfarin ... deficiency • Liver ... #Diagnosis #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... Lungs: • Pleural effusions ... pain • Swan neck ... Induced Lupus: • Symptoms
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... , fever, joint pain ... - infiltrates (anemia ... CLL -> Invade Skin ... #Oncology #Diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
, such as SLE, atherosclerotic ... , mucositis • Rash ... • Progressive symptoms ... Palpable purpura, joint ... #Diagnosis #Rheumatology
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... Constitutional symptoms ... pneumonia, pleural effusion ... 100% of cases), anemia ... #HIV #AIDS #pulmonary
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
vesicular eruption - Joints ... mucositis - Rash ... to exclude are infections ... vasculitis, and SLE ... #diagnosis #rheumatology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Hematologic malignancy ... (elevations of liver ... diarrhea, abdominal pain ... Bone Marrow - Anemia ... #differential #