9 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... deficiency • Liver ... Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... : INR/PT, aPTT(liver ... #Diagnosis #Causes ... #Workup #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early warfarin therapy ... Early liver disease ... #Causes #diagnosis ... #differential # ... hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Supratherapeutic warfarin ... • Reduced liver ... #Causes #diagnosis ... hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... DIC • Severe Liver ... #Coagulation #diagnosis ... #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Diagnosis Framework ... Acquired: • Heparin ... prolonged after ... discern these causes ... #Diagnosis #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
Thrombocytopenic Purpura ... be performed PT ... and decreased platelet ... WBC count and differential ... #Workup #Hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Causes purpura & ... coagulopathy & ↑bleeding ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
maculopapular rash ... Causes purpura & ... coagulopathy & ↑bleeding ... #Transfusions #diagnosis ... #management #hematology