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causes coagulation pt abnormal aptt bleeding bruising prolonged thrombocytopenia algorithm anticoagulant apixaban cascade classification clot comparison dabigatran deficiencies deficiency edoxaban
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Diagnosis Algorithm ... Platelet Function ... - Acquired • Anticoagulation ... Iatrogenic) • Liver ... #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Anticoagulants (Warfarin ... deficiency • Liver ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
, LMWH, warfarin ... ) • Advanced Liver ... Malignancy, Autoimmune disorders ... table #comparison #diagnosis ... #hematology #deficiency
Platelet Disorders - Differential Diagnosis Framework Qualitative Defects: • Adhesion • Aggregation • Secretion Quantitative Defects: • Production:
Platelet Disorders ... - Differential ... • Production: Liver ... #Disorders #Differential ... #Diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Disorders - Differential ... Diagnosis and Workup ... : INR/PT, aPTT(liver ... #Disorders #Differential ... #Workup #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
clot #PT #PTT #diagnosis ... #models #hematology ... pathophysiology #anticoagulation ... anticoagulant #Warfarin ... Rivaroxaban #Edoxaban #heparin
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... Diagnosis Framework ... Qualitative defect in platelets ... Acquired: • Heparin ... #Diagnosis #Hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Supratherapeutic warfarin ... • Reduced liver ... #differential # ... hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early warfarin therapy ... Early liver disease ... Prolonged #Causes #diagnosis ... #differential # ... hematology #coagulation
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Disorders • Nutritional ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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