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causes coagulation blood pt reactions activation bruising dic disseminated hemostasis hodgkins intravascular lymphoma macrophage mas oncology syndrome transfusion transfusions treatment
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... #PT #aPTT #Prolonged ... #Causes #diagnosis ... #differential # ... hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Supratherapeutic warfarin ... • Reduced liver ... #PT #aPTT #Prolonged ... hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/ABNORMAL PTT ... Acquired: • Heparin ... the PT remains prolonged ... PT/ABNORMAL PTT ... #Diagnosis #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... DIC • Severe Liver ... INR < 2.3 - APTT ... #Coagulation #diagnosis ... #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
maculopapular rash ... eruptions, diarrhea, liver ... coagulopathy & ↑bleeding ... #Transfusions #diagnosis ... #management #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... thrombocytopenia • Liver ... Fibrin degradation products ... #Management #Hematology ... #Rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... eruptions, diarrhea, liver ... Blood products contain ... #Transfusion #diagnosis ... #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
genes and gene products ... - Low Hb and platelets ... Immunohistochemical studies (to differentiate ... #hematology #oncology ... #management
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