23 results
Warfarin and DOAC Pharmacology
Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban
Target - Prodrug - Bioavailability
Warfarin and DOAC ... Pharmacology Warfarin ... Peak Effect (h) #Warfarin ... #DOAC #Pharmacology ... #NOAC #comparison
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Reversal Agents - Warfarin ... anticoagulation #doac ... #noac #pharmacology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Anticoagulant Agents Warfarin ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism ... #Pharmacology #
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... <2.5, but that drug ... #DOAC #Transitions ... Anticoagulation #Pharmacology
Comparison of oral anticoagulant agents (DOACS + Warfarin)

Reference: ENLS 2017 Pharmacotherapy. Neurocritical Care Journal.

#DOAC #Dosing #Oral
anticoagulant agents (DOACS ... + Warfarin) Reference ... #DOAC #Dosing #Oral ... Comparison #Table #Pharmacology
Direct-acting oral anticoagulants (DOACs) for VTE treatment and prevention - Comparison Table

#DOAC #Anticoagulants #Anticoagulation #VTE #Management
anticoagulants (DOACs ... ) for VTE treatment ... Comparison Table #DOAC ... VTE #Management #Pharmacology
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
anti-coagulation drugs ... Enoxaparin - Warfarin ... anticoagulation #pharmacology ... #medications #doac ... table #management #drugs
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
heparin #LMWH #NOAC ... #warfarin #coumadin ... Pradaxa #management #pharmacology
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
DOAC Cheat Sheet ... Dosing • Common Drug ... DeLoughery @Bloodman #DOAC ... #dosing #ckd #pharmacology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... anticoagulant treatment ... not available #DOAC ... #Reversal #NOAC ... hematology #management #pharmacology