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diagnosis management neurology clinical endocrinology hepatology mri radiology symptoms aflp algorithm amyotrophic biliary cardiology cholangitis cirrhosis comatose criticalcare deposition disease
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
• Myopathy (Also ... caused by hydroxychloroquine ... Erythematosus #SLE #MSK ... #pathophysiology ... #signs #symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... lateral sclerosis Pathophysiology ... - Causes progressive ... conditions listed in differential ... diagnosis column Treatment
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... , AKI, acute limb ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Management Summary Causes ... 5X ULN • AST/ALT ... AST declines > ALT ... HAGMA • Late complication
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
adenomas that require treatment ... of all sizes, it ... Signs / Symptoms ... / Complications ... mnemonic #GLFTAP #pathophysiology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... Findings: • ↑AST/ALT ... infiltration) Differential ... Monitor and Treat Complications
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... Nucleotidase • ALT ... obstruction • ALP
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology Pulse pressure is the difference between the systolic blood
Pulse Pressure - Differential ... Diagnosis and Pathophysiology ... • Sepsis Complications ... • Mitchell et al ... #Diagnosis #Pathophysiology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... Generalized fatigue - ALS ... test - Cogan sign ... - Peek sign ... immunologic assay - MuSK
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
conditions which all ... implications. ... Therefore, in all ... very mild if at all ... #diagnosis #differential
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