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management symptoms algorithm hepatology neurology causes abnormal clinical endocrinology hematology lfts liver mri radiology syndrome 1 aflp amyotrophic anorexianervosa arteritis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Diagnosis Algorithm ... • Severe - ALT ... Ischemia, AIH, Wilsons ... - CBD stone, Biliary
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... Nucleotidase • ALT ... obstruction • ALP ... bile ducts Differential
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
• Myopathy (Also ... Erythematosus #SLE #MSK ... #pathophysiology ... #signs #symptoms ... #diagnosis
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... : - Catch-all term ... Ill-appearing, vital sign ... Immunocompromised #Diagnosis ... Targetoid #Algorithm #Differential
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in all ... / Symptoms / Complications ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis ... #signs #symptoms
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
/ Symptoms / Complications ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #diagnosis #symptoms ... #signs
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... ) Summary ALS: combination ... lateral sclerosis Pathophysiology ... conditions listed in differential ... Treatment: - Multidisciplinary
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... , AKI, acute limb ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... #diagnosis #management
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
clinical symptoms/signs ... box indicates all ... include extrahepatic biliary ... ALP, alkaline phosphatase ... ; ALT, alanine aminotransferase
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... Findings: • ↑AST/ALT ... infiltration) Differential ... Diagnosis: Viral ... Monitor and Treat Complications
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