5 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Incidence: common in APL ... Prednisone 5mg/kg ... : >3 symptoms, or ... #diagnosis #management
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... , signs, and complications ... transformation into AML ... • Treatment algorithms ... #treatment #hematology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... complete paralysis of all ... than one after symptom ... Electrodiagnostic studies (Ex EMG ... #management #neurology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
have fever - ACS ... WBC >100k, + lab signs ... unless worrisome EKG ... Syndrome #TLS #diagnosis ... #management #hematology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
When present, symptoms ... • "Vasomotor" symptoms ... transformation into MDS or AML ... • Treatment algorithms ... #diagnosis #management